γ氨基丁酸运载蛋白2抗体
规格：1mg/1ml
英文名： GABA Transporter 2
别名： GABA transport protein; GAT 2; GAT-2; GAT2; Solute carrier family 6 (Neurotransmitter transporter, GABA), member 13; S6A13_HUMAN.
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GABA Tra
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
γ氨基丁酸运载蛋白2抗体产品介绍：background: GABA is a major inhibitory neurotransmitter and the GABAergic transmission is terminated by the rapid Na+/Cl-dependent uptake of through GABA transporters. There are multiple subtypes of GABA transporters (GAT1, GAT2, GAT3; and betaine GABA transporter (BGT-1). There is ~50% homology between each subtypes. GAT1 and GAT3 have been detected in various parts of the brain while GAT2 is found in many tissues. It appears that GAT1 and GAT3 are involved in distinct GABAergic transmission while γ氨基丁酸运载蛋白2抗体GAT2 may be important in non-neural functions. GAT2 is a gamma-amino butyric acid (GABA) transporter. It is a 602 amino acid (85kDa) transmembrane protein. Function: Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Subcellular Location: Membrane; Multi-pass membrane protein. Tissue Specificity: Expressed in brain, kidney, lung, liver and testis. Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily. Gene ID: 6540 Database links: Entrez Gene: 6540 γ氨基丁酸运载蛋白2抗体Human Entrez Gene: 14412 Mouse Entrez Gene: 171163 Rat SwissProt: Q8TCC2 Human SwissProt: Q9NSD5 Human SwissProt: P31649 Mouse SwissProt: P31646 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
γ氨基丁酸运载蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-200 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞膜受体 转运蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid