眼睛和头发颜色相关蛋白FUZ抗体
规格:1mg/1ml
英文名: FUZ/FUZZY
别名: FLJ22688; fuz; FUZZY_HUMAN; Fy; Protein fuzzy homolog.
分子量: 46kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FUZ/FUZZ
交叉反应:Human,
细胞定位:细胞浆
眼睛和头发颜色相关蛋白FUZ抗体产品介绍:background: FUZ is a 418 amino acid protein that localizes to both the cytoskeleton and the cytoplasm and is a human homolog of the Drosophila fuzzy protein. Existing as three alternatively spliced isoforms, FUZ is thought to be involved in regulating cytoskeletal function and may also play a role in maintaining cell polarity in epithelial cells. The gene encoding FUZ maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and眼睛和头发颜色相关蛋白FUZ抗体 leukocyte Ig-like receptors, several ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19. Function: Probable planar cell polarity effector involved in cilium biogenesis. May 眼睛和头发颜色相关蛋白FUZ抗体regulate protein and membrane transport to the cilium. May regulate the morphogenesis of hair follicles which depends on functional primary cilia. Subcellular Location: Cytoplasm. Cytoplasm; cytoskeleton. Similarity: Belongs to the fuzzy family. Database links: UniProtKB/Swiss-Prot: Q9BT04.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
眼睛和头发颜色相关蛋白FUZ抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid