FOXRED2蛋白抗体
规格：1mg/1ml
英文名： FOXRED2
别名： D15Bwg0759e; Endoplasmic reticulum flavoprotein associated with degradation; ERFAD; FAD dependent oxidoreductase domain containing 2; FAD-dependent oxidoreductase domain-containing protein 2; FLJ23322
分子量： 75kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FOXRED2
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆
FOXRED2蛋白抗体产品介绍：background: FOXRED2 is a 684 amino acid protein that exists as multiple alternatively spliced isoforms. The gene encoding FOXRED2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation FOXRED2蛋白抗体of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias. Function: Probable flavoprotein which may function in endoplasmic reticulum associated degradationFOXRED2蛋白抗体 (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation. Subunit: Interacts with SEL1L. May interact with OS9 and DNAJC10. Subcellular Location: Endoplasmic reticulum lumen. Post-translational modifications: N-glycosylated. Similarity: Belongs to the FOXRED2 family. Database links: UniProtKB/Swiss-Prot: Q8IWF2.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FOXRED2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 神经生物学 信号转导 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid