卵泡刺**结合蛋白1抗体
规格:1mg/1ml
英文名: FNIP1
别名: KIAA1961; FLCN-interacting protein; FNIP1; Folliculin interacting protein 1; FNIP1_HUMAN.
分子量: 130kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FNIP1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Horse, Sheep,
细胞定位:细胞浆
卵泡刺**结合蛋白1抗体产品介绍:background: May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. Function: May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1. Subunit: Forms homomultimers and heteromultimers with FNIP2.卵泡刺**结合蛋白1抗体 Interacts with FLCN (via C-terminus), with HSPCA and with the PRKAA1, PRKAB1 and PRKAG1 subunits of 5'-AMP-activated protein kinase (AMPK). Phosphorylated FLCN and AMPK are preferentially bound. Subcellular Location: Cytoplasm. Tissue Specificity: Strong expression is found in the heart, liver placenta, muscle, nasal mucosa, salivary gland and uvula and moderate expression in kidney and lung.卵泡刺**结合蛋白1抗体 Higher levels detected in clear cell renal cell carcinoma (RCC) and chromophobe RCC than in normal kidney tissue. Post-translational modifications: Phosphorylated by AMPK. Similarity: Belongs to the FNIP family. Gene ID: 96459 Database links: Entrez Gene: 96459 Human Omim: 610594 Human SwissProt: Q8TF40 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卵泡刺**结合蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 发育生物学 结合蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid