白细胞介素5抗体
规格：1mg/1ml
英文名： IL-5
别名： B Cell Differentiation Factor I; IL5; IL 5; Colony stimulating factor; Colony Stimulating Factor Eosinophil; EDF; Eosinophil; Eosinophil Differentiation Factor; IL 5; Interleukin 5; B-cell differentia
分子量： 13kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from rat IL-5
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
白细胞介素5抗体产品介绍：background: Interleukin 5 is a cytokine produced primarily by activated T lymphocytes. It exists as an antiparallel disulfide linked homodimeric glycoprotein with 115 amino acid residues in each chain. Known also as EDF (eosinophil differentiating factor), functions predominantly as an eosinophilopoietic factor. Analysis of its crystal structure reveals a novel two domain structure, with each domain showing significant homology to the cytokine fold in GMCSF, MCSF, IL2, IL4 and growth hormone. Human and mouse IL5 have 70% amino acid白细胞介素5抗体 sequence homology. Function: Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. Subunit: Homodimer; disulfide-linked. Subcellular Location: Secreted. Similarity: Belongs to the IL-5 family. Gene ID: 24497 Database白细胞介素5抗体 links: Entrez Gene: 3567 Human Omim: 147850 Human SwissProt: P05113 Human Unigene: 2247 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 白细胞介素-5（IL-5）的表达对嗜酸粒细胞（EOS）有浸润聚集的作用，目前多用变态反应方面的研究。 支气管**的重要特征主要是慢性非特异性炎症改变，其病因与发病机制十分复杂，白介素5在支气管**发病机理上，近年来受到了很大关注。
白细胞介素5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid