果糖胺-3激酶抗体
规格：1mg/1ml
英文名： FN3K
别名： EC 2.7.1.-; Ketosamine-3-kinase; FLJ12171; FN3K-related protein; FN3K-RP; FN3KL; FN3KRP; Fn3krp fructosamine-3-kinase-related protein; FN3X; Fructosamine-3-kinase-related protein; Ketosamine-3-kinase;
分子量： 35kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FN3K
交叉反应：Human, Mouse, Rat,
细胞定位：
果糖胺-3激酶抗体产品介绍：background: Amines, including those present on proteins, spontaneously react with glucose to make fructosamines in a reaction termed glycation. Fructosamine 3-kinase (FN3K), a 309-amino acid enzyme initially identified in erythrocytes, catalyzes the ATP-dependent phosphorylation of the third carbon on both D- and L-fructosamines, leading to their destabilization and eventually, their removal from the protein. FN3K is a monomer that is ubiquitously expressed in mammalian tissue and phosphorylates both low molecular 果糖胺-3激酶抗体mass and protein-bound fructosamines which are formed as a result of glycation of glucose with primary amines. FN3K protects proteins from the harmful effects of nonenzymatic glycation, and may also be involved in peptide repair and cell metabolism. FN3KRP (fructosamine-3-kinase-related protein) is a 309 amino acid protein that is expressed in erythrocytes, bone marrow, spleen, brain and kidney and belongs to the fructosamine kinase family. FN3KRP functions to phosphorylate psicoamines and ribulosamines on the third carbon of their sugar moiety, thereby leading to 果糖胺-3激酶抗体the deglycation of the target amines. Function: May initiate a process leading to the deglycation of fructoselysine and of glycated proteins. May play a role in the phosphorylation of 1-deoxy-1-morpholinofructose (DMF), fructoselysine, fructoseglycine, fructose and glycated lysozyme. Subunit: Monomer (Probable). Tissue Specificity: Expressed in erythrocytes. Similarity: Belongs to the fructosamine kinase family. Database links: UniProtKB/Swiss-Prot: Q9H479.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
果糖胺-3激酶抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid