软骨细胞Ezrin样蛋白抗体
规格：1mg/1ml
英文名： FARP1
别名： CDEP; Chondrocyte derived ezrin like protein; FERM RhoGEF and pleckstrin domain containing protein 1; FERM RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived). PLEKHC2; FARP1_HUMAN.
分子量： 119kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FARP1
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
软骨细胞Ezrin样蛋白抗体产品介绍：background: FARP1 (FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1), also known as PLEKHC2 or CDEP, is a 1,045 amino acid protein that contains one FERM domain, one DH domain and two PH domains. Existing as multiple alternatively spliced isoforms that are expressed in fetal heart, brain and spleen, as well as in ***** lung, kidney and testis, FARP1 is thought to function as a Rho-guanine nucleotide exchange factor that may play a role in linking the cell membrane to the cytoskeleton. The gene encoding FARP1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 软骨细胞Ezrin样蛋白抗体13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. Function: The FARP1 protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain, and is believed to be a member of the band 4.1 superfamily, whose members link the软骨细胞Ezrin样蛋白抗体 cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for the FARP1 gene, which shows increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. Subcellular Location: Cytoplasmic. Similarity: Contains 1 DH (DBL-homology) domain. Contains 1 FERM domain. Contains 2 PH domains. Database links: UniProtKB/Swiss-Prot: Q9Y4F1.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
软骨细胞Ezrin样蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 细胞类型标志物 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid