磷酸化Ets转录因子家族ets1抗体
规格:1mg/1ml
英文名: phospho-ETS1 (Thr38)
别名: ETS1 (phospho T38); ETS1 (phospho Thr38); p-ETS1 (phospho T38); Avian erythroblastosis virus E26 (v ets) oncogene homolog 1; C ets 1 protein; ETS 1; Ets protein; ETS1; ETS-1; ETS1 protein; ETS1_HUMAN;
分子量: 49kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthesised phosphopeptide derived from human
交叉反应:Human, Mouse,
细胞定位:细胞核
磷酸化Ets转录因子家族ets1抗体产品介绍:background: This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene磷酸化Ets转录因子家族ets1抗体.[provided by RefSeq, Jul 2011]. Function: Transcription factor. Subunit: Interacts with MAF and MAFB. Interacts with PAX5, the interaction alters DNA-binding properties. Binds to DAXX. Interacts with UBE2I. Subcellular Location: Nucleus. Post-translational modifications: Sumoylated on Lys-15 and Lys-227, preferentially with SUMO2; which inhibits transcriptional activity. Ubiquitinated; which induces 磷酸化Ets转录因子家族ets1抗体proteasomal degradation. Similarity: Belongs to the ETS family. Contains 1 ETS DNA-binding domain. Contains 1 PNT (pointed) domain. Database links: UniProtKB/Swiss-Prot: P14921.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化Ets转录因子家族ets1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid