DNA聚合酶δ2/DNA pol δ 2抗体
规格：1mg/1ml
英文名： DNA polymerase delta p50
别名： DNA polymerase delta subunit 2; DNA polymerase delta subunit p50; DNA polymerase subunit delta 2; DNA polymerase subunit delta p50; DPOD2_HUMAN; POLD 2; POLD2.
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DNA poly
交叉反应：Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Macaque Monkey
细胞定位：细胞核
DNA聚合酶δ2/DNA pol δ 2抗体产品介绍：background: This gene encodes the 50-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigeDNA聚合酶δ2/DNA pol δ 2抗体n (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Mar 2012]. Function: The function of the small subunit is not yet clear. Subunit: Heterotetramer composed of subunits of 125 DNA聚合酶δ2/DNA pol δ 2抗体kDa, 50 kDa, 66 kDa and 12 kDa. Interacts with KCTD10 (By similarity). Interacts with KCTD13/POLDIP1, POLDIP2 and POLDIP3. Interacts with WRNIP1. Interacts with POLD4. Subcellular Location: Nucleus. Similarity: Belongs to the DNA polymerase delta/II small subunit family. Database links: UniProtKB/Swiss-Prot: P49005.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA聚合酶δ2/DNA pol δ 2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 细胞周期蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid