冷休克蛋白DBPA抗体
规格：1mg/1ml
英文名： DBPA
别名： Cold shock domain containing protein A; Cold shock domain-containing protein A; csdA; CSDA1; DBPA; DNA binding protein A; DNA-binding protein A; Single strand DNA binding protein NF GMB; Single-strand
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human DBPA/CSD
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
冷休克蛋白DBPA抗体产品介绍：background: CSDA is a 372 amino acid nuclear and cytoplasmic protein that is highly expressed in skeletal muscle and heart. Containing one CSD (cold-shock) domain, CSDA is thought to bind to GM-CSF promoter, full length mRNA and to short RNA sequences containing a specific consensus site. CSDA is suggested to have a role in translation repression and is found in a mRNP complex with MSY2. MSY2 belongs to the Y-box family of multifunctional proteins that regulate both transcription and translation. CSDA participates in promoting cell proliferation and expression of cyclin D1 and proliferating cell nuclear antigen (PCNA). CSDA is regarded to be an important component of the 冷休克蛋白DBPA抗体mechanisms that sense epithelial density and in regulating the switch between proliferation and differentiation through complex transcriptional networks. Function: Binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression. Subcellular Location: Cytoplasm. Nucleus.冷休克蛋白DBPA抗体 Tissue Specificity: Highly expressed in skeletal muscle and heart. Similarity: Contains 1 CSD (cold-shock) domain. Gene ID: 8531 Database links: Entrez Gene: 8531 Human Entrez Gene: 56449 Mouse Entrez Gene: 83807 Rat Omim: 603437 Human SwissProt: P16989 Human SwissProt: Q61478 Mouse SwissProt: Q68G78 Mouse SwissProt: Q8BPG0 Mouse SwissProt: Q9JKB3 Mouse SwissProt: Q3KRC7 Rat SwissProt: Q62764 Rat Unigene: 221889 Human Unigene: 299604 Mouse Unigene: 458000 Mouse Unigene: 3306 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
冷休克蛋白DBPA抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞周期蛋白 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid