转录起始因子TFIID亚基9b/神经细胞死亡相关蛋白7抗体
规格：1mg/1ml
英文名： TAF9b/DN7
别名： DN-7; DN7; Neuronal cell death related protein 7; Neuronal cell death-related protein 7; TAF9-like RNA polymerase II TBP associated factor, 31 kD; Taf9b; TAF9B RNA polymerase II, TATA box binding prot
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TAF9b/DN
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, Chimpanzee,
细胞定位：细胞核
转录起始因子TFIID亚基9b/神经细胞死亡相关蛋白7抗体产品介绍：background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar转录起始因子TFIID亚基9b/神经细胞死亡相关蛋白7抗体 to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process. [provided by RefSeq, Jul 2008] Function: Essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. May have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free转录起始因子TFIID亚基9b/神经细胞死亡相关蛋白7抗体 TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription. Subcellular Location: Nucleus. Similarity: Belongs to the TAF9 family. Database links: Entrez Gene: 538983 Cow Entrez Gene: 51616 Human Entrez Gene: 407786 Mouse Entrez Gene: 171152 Rat Omim: 300754 Human SwissProt: Q9HBM6 Human SwissProt: Q6NZA9 Mouse SwissProt: Q62880 Rat Unigene: 592248 Human Unigene: 19440 Mouse Unigene: 11270 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录起始因子TFIID亚基9b/神经细胞死亡相关蛋白7抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid