锌指蛋白851抗体
规格：1mg/1ml
英文名： BTBD15
别名： BTB (POZ) domain containing 15; BTB/POZ domain-containing protein 15; BTBD15; HSPC063; MGC26123; MGC57431; MGC60348; MGC88058; OTTHUMP00000230934; OTTHUMP00000230935; OTTHUMP00000230937; OTTHUMP000002
分子量： 64kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZBTB44
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
锌指蛋白851抗体产品介绍：background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying protein. ZBTB44 is a 570 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB44 contains a BTB domain, also锌指蛋白851抗体 known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB44 functions as a transcription regulator. Four isoforms of ZBTB44 have been identified. Function: May be involved in transcriptional regulation. Subcellular Location: Nucleus. Post-translational modifications: modificationsPhosphorylated upon DNA damage, probably 锌指蛋白851抗体by ATM or ATR. Similarity: Contains 1 BTB (POZ) domain. Contains 4 C2H2-type zinc fingers. Database links: Entrez Gene: 29068 Human SwissProt: Q8NCP5 Human Unigene: 178499 Human Unigene: 728154 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白851抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid