T**细胞受体γ链2蛋白C抗体
规格：1mg/1ml
英文名： TCRGC2
别名： T Cell Receptor V gamma 3; T cell rearranging gene gamma; T cell receptor gamma locus; T-cell receptor gamma chain C region PT-gamma-1/2; T-cell receptor gamma-2 chain C region; tcrg; TCRGC2; trg; TRG
分子量： 22kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TCRGC2
交叉反应：Human,
细胞定位：细胞膜
T**细胞受体γ链2蛋白C抗体产品介绍：background: T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable) , J (joining), and C (constant) segments. During T cell development, the gamma chain isT**细胞受体γ链2蛋白C抗体 synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. T**细胞受体γ链2蛋白C抗体Several V segments of the gamma locus are known to be incapable of encoding a protein and are considered pseudogenes. Somatic rearrangment of the gamma locus has been observed in T cells derived from patients with T cell leukemia and ataxia telangiectasia. Subcellular Location: Membrane; Single-pass membrane protein Gene ID: 6967 Database links: Entrez Gene: 6967 Human SwissProt: P03986 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
T**细胞受体γ链2蛋白C抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞膜受体 **细胞 t-**细胞 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid