锌指蛋白592抗体
规格：1mg/1ml
英文名： ZNF592
别名： 8430405N24; A730014M16Rik; CAMOS; KIAA0211; MGC138437; MGC138439; mKIAA0211; SCAR5; Zfp592; Zinc finger protein 592; ZNF 592; ZNF592.
分子量： 137kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNF592
交叉反应：Human, Mouse,
细胞定位：细胞核
锌指蛋白592抗体产品介绍：background: This gene is thought to play a role in a complex developmental pathway and the regulation of genes involved in cerebellar development. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia. [provided by RefSeq, Jan 2011] Function: May be involved in transcriptional regulation. Subcellular Location: Nuclear. Tissue Specificity: Widely expressed, with highest levels in skeletal muscle. Expressed throughout the central nervous system, including in the cerebellum and cerebellar 锌指蛋白592抗体vermis, with higher expression in the substantia nigra. Widely expressed in fetal tissues. DISEASE: The disease is caused by mutations affecting the gene represented in this entry. Disease description:Spinocerebellar ataxia defines a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, 锌指蛋白592抗体due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCAR5 patients show developmental delay, psychomotor retardation, proportionate short stature, cerebellar spastic ataxia, microcephaly, optic atrophy, speech defect, abnormal osmiophilic pattern of skin vessels and cerebellar atrophy. Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 13 C2H2-type zinc fingers. Database links: Entrez Gene: 9640 Human Omim: 613624 Human SwissProt: Q92610 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白592抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：神经生物学 转录调节因子 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid