卵透明带糖蛋白1抗体
规格：1mg/1ml
英文名： ZP1
别名： MGC87693; Processed zona pellucida sperm-binding protein 1; zona pellucida glycoprotein 1 (sperm receptor); Zona pellucida glycoprotein 1; zona pellucida protein 1; Zp 1; Zp-1; Zp1; ZP1_HUMAN.
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZP1
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：分泌型蛋白
卵透明带糖蛋白1抗体产品介绍：background: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. [provided by RefSeq, May 2014] Function: The mammalian zona pellucida, which mediates species-specific sperm binding,卵透明带糖蛋白1抗体 induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP1 ensures the structural integrity of the zona pellucida. Subunit: Polymers of ZP2 and ZP3 organized into long filaments cross-linked by ZP1 homodimers. Subcellular Location: Secreted > extracellular space > extracellular matrix and Cell membrane. Tissue Specificity卵透明带糖蛋白1抗体 Oocytes. Post-translational modifications: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida. O-glycosylated. Similarity: Belongs to the ZP domain family. ZPB subfamily. Contains 1 P-type (trefoil) domain. Contains 1 ZP domain. Gene ID: 22917 Database links: Entrez Gene: 22917 Human Omim: 195000 Human SwissProt: P60852 Human Unigene: 172130 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
卵透明带糖蛋白1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 干细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid