液泡蛋白分选蛋白45A抗体
规格：1mg/1ml
英文名： VPS45A
别名： h-VPS45; H1; H1VPS45; HGNC:14579; hlVps45; Leucocyte vacuolar protein sorting 45; OTTHUMP00000014482; Vacuolar protein sorting 45 homolog (S. cerevisiae); Vacuolar protein sorting 45A (yeast homolog);
分子量： 65kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VPS45A
交叉反应：Human, Mouse, Rat, Chicken, Dog,
细胞定位：细胞膜
液泡蛋白分选蛋白45A抗体产品介绍：background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by 液泡蛋白分选蛋白45A抗体RefSeq, Jul 2013] Function: May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. Subcellular Location: Golgi apparatus membrane. Endosome membrane. Associated with Golgi/endosomal vesicles and the trans-Golgi network. Tissue Specificity: Ubiquitous. Expression was highest in testis, heart and brain, intermediate in kidney, spleen, prostate, ovary, 液泡蛋白分选蛋白45A抗体small intestine and thymus and low in lung, skeletal muscle, placenta, colon, pancreas, peripheral blood leukocytes and liver. Similarity: Belongs to the STXBP/unc-18/SEC1 family. Database links: Entrez Gene: 430741 Chicken Entrez Gene: 11311 Human Entrez Gene: 22365 Mouse Entrez Gene: 64516 Rat Omim: 610035 Human SwissProt: Q9NRW7 Human SwissProt: P97390 Mouse SwissProt: O08700 Rat Unigene: 443750 Human Unigene: 263185 Mouse Unigene: 9316 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
液泡蛋白分选蛋白45A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 跨膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit