液泡蛋白分选蛋白36抗体
规格：1mg/1ml
英文名： VPS36
别名： C13orf9; CGI 145; EAP45; ELL associated protein of 45 kDa; ELL-associated protein of 45 kDa; ESCRT-II complex subunit VPS36; Vacuolar protein sorting associated protein 36; Vacuolar protein-sorting-as
分子量： 44kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VPS36
交叉反应：Human, Mouse, Rat, Chicken, Rabbit, Guinea Pig,
细胞定位：细胞核 细胞浆 细胞膜
液泡蛋白分选蛋白36抗体产品介绍：background: This gene encodes a protein that is a subunit of the endosomal sorting complex required for transport II (ESCRT-II). This protein complex functions in sorting of ubiquitinated membrane proteins during endocytosis. A similar protein complex in rat is associated with RNA polymerase elongation factor II. [provided by RefSeq, Aug 2013] Function: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation液泡蛋白分选蛋白36抗体. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. Binds phosphoinosides such as PtdIns(3,4,5)P3. Subcellular Location: Cytoplasm. Endosome. Late endosome. Membrane. Nucleus. Colocalizes with ubiquitinated proteins on late endosomes. Recruited to the endosome membrane to participate in液泡蛋白分选蛋白36抗体 vesicle formation. Similarity: Belongs to the VPS36 family. Contains 1 GLUE domain. Database links: Entrez Gene: 418883 Chicken Entrez Gene: 511223 Cow Entrez Gene: 477292 Dog Entrez Gene: 51028 Human Entrez Gene: 70160 Mouse Entrez Gene: 290851 Rat Entrez Gene: 335810 Zebrafish Omim: 610903 Human SwissProt: A5PK00 Cow SwissProt: Q86VN1 Human SwissProt: Q91XD6 Mouse SwissProt: P0C0A2 Rat SwissProt: Q7ZVK4 Zebrafish Unigene: 109520 Human Unigene: 41453 Mouse Unigene: 474298 Mouse Unigene: 12707 Rat Unigene: 21065 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
液泡蛋白分选蛋白36抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 泛素
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid