液泡蛋白分选蛋白35抗体
规格：1mg/1ml
英文名： VPS35
别名： DKFZp434E1211; DKFZp434P1672; FLJ10752; FLJ13588; FLJ20388; hVPS35; Maternal embryonic 3; Maternal-embryonic 3; MEM 3; MEM3; PARK17; TCCCTA00141; Vacuolar protein sorting 35 (yeast); Vacuolar protein
分子量： 91kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human VPS35
交叉反应：Human, Mouse, Rat, Rabbit,
液泡蛋白分选蛋白35抗体细胞定位：细胞浆 细胞膜
产品介绍：background: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex.液泡蛋白分选蛋白35抗体 [provided by RefSeq, Jul 2008] Function: Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Subcellular Location: Cytoplasm. Membrane. Tissue Specificity: Ubiquitous. Highly expressed in液泡蛋白分选蛋白35抗体 heart, brain, placenta, skeletal muscle, spleen, thymus, testis, ovary, small intestine, kidney and colon. Similarity: Belongs to the VPS35 family. Database links: Entrez Gene: 521864 Cow Entrez Gene: 100133770 Human Entrez Gene: 55737 Human Entrez Gene: 65114 Mouse Entrez Gene: 25479 Rat Omim: 601501 Human SwissProt: Q2HJG5 Cow SwissProt: Q96QK1 Human SwissProt: Q9EQH3 Mouse Unigene: 454528 Human Unigene: 296520 Mouse Unigene: 391632 Mouse Unigene: 161720 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
液泡蛋白分选蛋白35抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid