DNA聚合酶α3抗体
规格：1mg/1ml
英文名： POLD3
别名： DNA polymerase delta subunit 3; DNA polymerase delta subunit p66; DNA polymerase delta, subunit 3; DNA polymerase subunit delta p66; DPOD3_HUMAN; KIAA0039; P66; P68; Pol delta C subunit (p66); Pold3;
分子量： 51kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human POLD3
交叉反应：Human, Mouse, Dog, Pig, Rabbit,
细胞定位：细胞核
DNA聚合酶α3抗体产品介绍：background: This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012] DNA聚合酶α3抗体Function: Required for optimal DNA polymerase delta activity. Subunit: Heterotetramer composed of subunits of DNA聚合酶α3抗体125 kDa, 50 kDa, 66 kDa and 12 kDa. Interacts with POLD2. Interacts with PCNA. Subcellular Location: Nucleus. Database links: Entrez Gene: 10714 Human Omim: 611415 Human SwissProt: Q15054 Human Unigene: 82502 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
DNA聚合酶α3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid