神经丛蛋白D1抗体
规格:1mg/1ml
英文名: Plexin D1
别名: KIAA0620; MGC75353; PLEX D1; PLEXD 1; PLEXD1; Plexin-D1; PlexinD1; PLXD1_HUMAN; PLXN D1; PLXND 1; PLXND1; PLXND1 protein.
分子量: 208kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Plexin D
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位:细胞膜
神经丛蛋白D1抗体产品介绍:Function: Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature (By similarity). Mediates anti-angiogenic signaling in response to SEMA3E. Subunit: 神经丛蛋白D1抗体Interacts with NRP1, SEMA4A, SEMA3A, SEMA3C and SEMA3E. Subcellular Location: Cell membrane. Tissue Specificity: Detected at low levels in heart, placenta, lung, skeletal muscle, kidney, thymus and liver. Detected at very low levels in brain, colon, spleen, small intestine and peripheral blood leukocytes. Similarity: Belongs to the plexin family. Contains 3 IPT/TIG domains. Contains 1 Sema domain. Gene ID: 神经丛蛋白D1抗体23129 Database links: Entrez Gene: 23129 Human Entrez Gene: 67784 Mouse Omim: 604282 Human SwissProt: Q9Y4D7 Human SwissProt: Q3UH93 Mouse SwissProt: Q68HV1 Mouse SwissProt: Q8VCL8 Mouse SwissProt: Q9CZF2 Mouse Unigene: 301685 Human Unigene: 3085 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
神经丛蛋白D1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:心血管 细胞生物 神经生物学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid