桥粒斑菲素蛋白3抗体
规格：1mg/1ml
英文名： Plakophilin 3
别名： PKP 3 ; PKP3 ; PKP3_HUMAN ; Plakophilin 3b ; Plakophilin-3 ; Plakophilin3.
分子量： 87kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Plakophi
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位：细胞核
桥粒斑菲素蛋白3抗体产品介绍：background: This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014] Function: May play a role in junctional 桥粒斑菲素蛋白3抗体plaques. Subcellular Location: Nucleus. Cell junction > desmosome. Nuclear and associated with desmosomes. Tissue Specificity: Found in desmosomes of most simple and stratified epithelia. Not found in foreskin fibroblasts and various sarcoma-derived cell lines.桥粒斑菲素蛋白3抗体 Beside dendritic reticular cells of lymphatic follicles not found in non-epithelial desmosome-bearing tissues. Similarity: Belongs to the beta-catenin family. Contains 8 ARM repeats. Gene ID: 11187 Database links: Entrez Gene: 11187 Human Entrez Gene: 56460 Mouse Entrez Gene: 293619 Rat Omim: 605561 Human SwissProt: Q9Y446 Human SwissProt: Q9QY23 Mouse Unigene: 534395 Human Unigene: 350037 Mouse Unigene: 144803 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
桥粒斑菲素蛋白3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid