巨噬细胞炎性蛋白MIP-3a抗体
规格：1mg/1ml
英文名： Macrophage Inflammatory Protein 3 alpha
别名： Beta-chemokine exodus-1; C-C motif chemokine 20; CC chemokine LARC; CCL20; CCL20(2-70); CCL20_HUMAN; Chemokine (C C motif) ligand 20; Chemokine CC motif ligand 20; CKb4; Exodus 1; LARC; Liver and acti
分子量： 8.6kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCL20
交叉反应：Human, Mouse, Rat,
细胞定位：分泌型蛋白
巨噬细胞炎性蛋白MIP-3a抗体产品介绍：background: This antimicrobial gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene displays chemotactic activity for lymphocytes and can repress proliferation of myeloid progenitors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014]. Function: Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards 巨噬细胞炎性蛋白MIP-3a抗体epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. Subunit: Binds to and activate CCR6. Subcellular Location: Secreted. Tissue Specificity: Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus,巨噬细胞炎性蛋白MIP-3a抗体 prostate, testis, small intestine and colon. Post-translational modifications: C-terminal processed forms which lack 1, 3 or 6 amino acids are produced by proteolytic cleavage after secretion from peripheral blood monocytes. Similarity: Belongs to the intercrine beta (chemokine CC) family. Gene ID: 6364 Database links: Entrez Gene: 6364 Human Entrez Gene: 20297 Mouse Entrez Gene: 29538 Rat Omim: 601960 Human SwissProt: P78556 Human SwissProt: O89093 Mouse SwissProt: P97884 Rat Unigene: 75498 Human Unigene: 116739 Mouse Unigene: 10722 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
巨噬细胞炎性蛋白MIP-3a抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid