膜类胰蛋白酶1抗体
规格：1mg/1ml
英文名： TPSG1
别名： gamma I; gamma II; lung tryptase; mast cell protease II; mast cell tryptase; pituitary tryptase; PRSS31; Serine protease 31; skin tryptase; TMT; Tpsg1; Transmembrane tryptase; trpA; TRYG1_HUMAN; Trypt
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TPSG1
交叉反应：Human, Mouse,
细胞定位：细胞膜
膜类胰蛋白酶1抗体产品介绍：background: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells;膜类胰蛋白酶1抗体 whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008] Subcellular Location: Membrane. Tissue Specificity: 膜类胰蛋白酶1抗体Expressed in many tissues. Similarity: Belongs to the peptidase S1 family. Tryptase subfamily. Contains 1 peptidase S1 domain. Database links: Entrez Gene: 25823 Human Entrez Gene: 26945 Mouse Entrez Gene: 302990 Rat Omim: 609341 Human SwissProt: Q9NRR2 Human SwissProt: Q9QUL7 Mouse Unigene: 592076 Human Unigene: 180108 Mouse Unigene: 163109 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
膜类胰蛋白酶1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 泛素 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid