囊泡相关膜蛋白4抗体
规格:1mg/1ml
英文名: VAMP4
别名: VAMP 24; VAMP 4; VAMP-4; VAMP24; VAMP4; VAMP4 protein; VAMP4_HUMAN; Vesicle associated membrane protein 4; Vesicle associated membrane protein 4 isoform CRA a; Vesicle associated membrane protein 4 is
分子量: 18kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human VAMP4
交叉反应:Human, Mouse, Rat,
细胞定位:
囊泡相关膜蛋白4抗体产品介绍:background: Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008] Function: Involved in the pathway that functions to 囊泡相关膜蛋白4抗体remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule. Subcellular Location: Golgi apparatus > trans-Golgi network membrane. Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found 囊泡相关膜蛋白4抗体on the mature secretory organelles. Similarity: Belongs to the synaptobrevin family. Contains 1 v-SNARE coiled-coil homology domain. Database links: Entrez Gene: 8674 Human Entrez Gene: 53330 Mouse Entrez Gene: 364033 Rat Omim: 606909 Human SwissProt: A2IDD8 Human SwissProt: O75379 Human SwissProt: O70480 Mouse Unigene: 6651 Human Unigene: 10699 Mouse Unigene: 105555 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
囊泡相关膜蛋白4抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 神经生物学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid