小核糖核蛋白SNRPB抗体
规格：1mg/1ml
英文名： SNRPB
别名： B polypeptide of Sm protein; COD; RSMB_HUMAN; Sm B/B'; Sm B/Sm B'; Sm B/SmB'; Sm protein B/B''; Sm-B/B''; Small nuclear ribonucleoprotein polypeptide B; Small nuclear ribonucleoprotein polypeptide B/B
分子量： 24kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SNRPB
交叉反应：Human, Mouse, Rat, Chicken, Dog, Rabbit, Guinea Pig,
细胞定位：细胞核
小核糖核蛋白SNRPB抗体产品介绍：background: The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.小核糖核蛋白SNRPB抗体 [provided by RefSeq, Jul 2008] Function: Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Associated with snRNP U1, U2, U4/U6 and U5. May have a functional role in the pre-mRNA splicing or in snRNP structure. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner. Subcellular Location: Nucleus. Post-translational modifications:小核糖核蛋白SNRPB抗体 Methylated. Arg-108 and Arg-112 are dimethylated, probably to asymmetric dimethylarginine. Similarity: Belongs to the snRNP SmB/SmN family. Database links: Entrez Gene: 6628 Human Entrez Gene: 20638 Mouse Entrez Gene: 171365 Rat Omim: 182282 Human SwissProt: P14678 Human SwissProt: P27048 Mouse SwissProt: P17136 Rat Unigene: 83753 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
小核糖核蛋白SNRPB抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid