SMCR7L蛋白抗体
规格：1mg/1ml
英文名： SMCR7L
别名： dJ1104E15.3; HSU79252; Hypothetical protein LOC54471; MID51; MIEF1; mitochondrial dynamic protein MID51; mitochondrial dynamic protein of 51 kDa; mitochondrial dynamics protein MID51; mitochondrial dy
分子量： 51kDa
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SMCR7L
交叉反应：Human, Mouse, Rat, Rabbit, Guinea Pig,
细胞定位：细胞膜
SMCR7L蛋白抗体产品介绍：Function: Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADPSMCR7L蛋白抗体 to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L. Subcellular Location: Membrane. Tissue Specificity: Expression is relatively high in heart, skeletal muscle, pancreas and kidney. Similarity: Belongs to the SMCR7SMCR7L蛋白抗体 family. Database links: Entrez Gene: 54471 Human Entrez Gene: 239555 Mouse Entrez Gene: 315141 Rat Omim: 615497 Human SwissProt: Q9NQG6 Human SwissProt: Q8BGV8 Mouse SwissProt: Q5XIS8 Rat Unigene: 714252 Human Unigene: 728085 Human Unigene: 307163 Mouse Unigene: 62655 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SMCR7L蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 发育生物学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid