SMCR7蛋白抗体
规格:1mg/1ml
英文名: SMCR7
别名: MGC23130; MID49; MIEF2; Mitochondrial dynamic protein MID49; Mitochondrial dynamic protein of 49 kDa; Mitochondrial elongation factor 2; Smith Magenis syndrome chromosome region candidate 7; Smith-Mag
分子量: 49kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human SMCR7
交叉反应:Human, Mouse,
细胞定位:
SMCR7蛋白抗体产品介绍:background: This gene encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011] Function: Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes theSMCR7蛋白抗体 recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity. Subcellular Location: Mitochondrion outer membrane; Single-pass membrane protein. Colocalizes with DNM1L at mitochondrial membrane. Forms foci and rings around mitochondria. Tissue Specificity: SMCR7蛋白抗体Expressed in all tissues tested with highest expression in heart and skeletal muscle. Similarity: Belongs to the MID49/MID51 family. Database links: Entrez Gene: 125170 Human Entrez Gene: 497916 Rat SwissProt: Q96C03 Human Unigene: 655555 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
SMCR7蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 发育生物学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid