果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体
规格：1mg/1ml
英文名： PFKFB3/PFK2
别名： 6 phosphofructo 2 kinase/ fructose 2,6 bisphosphatase; 6 phosphofructo 2 kinase/fructose 2,6 biphosphatase 3; 6-bisphosphatase; 6-P2ase 3; 6-P2ASE brain/placenta-type isozyme; 6PF 2 K/Fru 2,6 P2ASE br
分子量： 58kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PFKFB3
交叉反应：Human, Mouse, Rat,
细胞定位：
果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体产品介绍：background: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] Function: Synthesis and degradation of fructose 2,6-bisphosphate. Tissue Specificity: Ubiquitous. Post-translational modifications: 果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体Phosphorylation by AMPK stimulates activity. Similarity: In the C-terminal section; belongs to the phosphoglycerate mutase family. Database links: Entrez Gene: 5207 Human Entrez Gene: 5208 Human Entrez Gene: 5209 Human Entrez Gene: 5210 Human Entrez Gene: 170768 Mouse Entrez Gene: 18639 Mouse Entrez Gene: 18640 Mouse Entrez Gene: 270198 Mouse Entrez Gene: 117276 Rat Entrez Gene: 24638 Rat Entrez Gene: 24640 Rat Entrez Gene: 54283 Rat Omim: 605319 Human SwissProt: O60825 Human SwissProt: P16118 Human SwissProt: Q16875 Human SwissProt: Q16877 Human SwissProt: P70265 Mouse SwissProt: P70266 Mouse SwissProt: Q6DTY7 Mouse SwissProt: O35552 Rat果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体 SwissProt: P07953 Rat SwissProt: P25114 Rat SwissProt: Q9JJH5 Rat Unigene: 195471 Human Unigene: 282702 Human Unigene: 444304 Human Unigene: 476217 Human Unigene: 132391 Mouse Unigene: 249131 Mouse Unigene: 249861 Mouse Unigene: 10115 Rat Unigene: 10791 Rat Unigene: 44844 Rat Unigene: 90092 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid