前折叠蛋白亚基5抗体
规格:1mg/1ml
英文名: PFDN5
别名: 1190001O17Rik; 1700010A06Rik; c myc binding protein; c-myc binding protein MM 1; C-myc-binding protein Mm-1; D15Ertd697e; EIG 1; Eig1; MGC5329; MGC71907; MM 1; MM1; Myc modulator 1; PFD5; PFD5_HUMAN;
分子量: 17kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human PFDN5
交叉反应:Human, Mouse, Rat,
细胞定位:
前折叠蛋白亚基5抗体产品介绍:background: This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] Function: Binds specifically to cytosolic chaperonin (c-CPN) 前折叠蛋白亚基5抗体and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Tissue Specificity: Highly expressed in pancreas and skeletal muscle and moderately in前折叠蛋白亚基5抗体 other tissues. Similarity: Belongs to the prefoldin subunit alpha family. Database links: Entrez Gene: 5204 Human Entrez Gene: 56612 Mouse Entrez Gene: 300257 Rat Omim: 604899 Human SwissProt: Q99471 Human SwissProt: Q9WU28 Mouse Unigene: 655327 Human Unigene: 158264 Mouse Unigene: 3401 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
前折叠蛋白亚基5抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 转录调节因子 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid