雄**诱导细胞增殖抑制蛋白抗体
规格：1mg/1ml
英文名： PDS5B
别名： AI646570; Androgen induced proliferation inhibitor; Androgen-induced prostate proliferative shutoff associated protein AS3; APRIN; AS3; AW212954; CG008; FLJ23236; KIAA0979; mKIAA0979; PDS5, regulator
分子量： 165kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PDS5B
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
雄**诱导细胞增殖抑制蛋白抗体产品介绍：background: This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq, May 2010] Function: Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May 雄**诱导细胞增殖抑制蛋白抗体couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells. Subunit: Interacts with the cohesin complex. Interacts with RAD21; the interaction is direct. Interacts with WAPAL (via FGF motifs) or CDCA5 (via the FGF motif); the interaction is direct, cohesin-dependent and competitive (Probable). Subcellular Location: Nuclear Tissue Specificity: 雄**诱导细胞增殖抑制蛋白抗体Widely expressed. Similarity: Belongs to the PDS5 family. Contains 3 A.T hook DNA-binding domains. Contains 1 HEAT repeat. Gene ID: 23047 Database links: Entrez Gene: 418910 Chicken Entrez Gene: 23047 Human Entrez Gene: 100710 Mouse Entrez Gene: 304218 Rat Entrez Gene: 100135353 Xenopus tropicalis Omim: 605333 Human SwissProt: Q5F3U9 Chicken SwissProt: Q9NTI5 Human SwissProt: Q4VA53 Mouse SwissProt: Q6TRW4 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
雄**诱导细胞增殖抑制蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 细胞周期蛋白 细胞分化
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid