CP2相关转录抑制因子1抗体
规格:1mg/1ml
英文名: CRTR1
别名: CP2 related transcriptional repressor 1; CP2-related transcriptional repressor 1; CRTR 1; CRTR-1; LBP 9; LBP9; TF2L1_HUMAN; TFCP2 L1; TFCP2L1; Transcription factor CP2 like 1; Transcription factor CP2
分子量: 55kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human CRTR1
交叉反应:Human, Mouse, Rat, Chicken, Dog, Cow, Horse,
细胞定位:细胞核
CP2相关转录抑制因子1抗体产品介绍:background: The long terminal repeat binding protein-1 (LBP-1) mammalian family of transcription factors are proteins that stimulate transcription in HeLa cells from the major late promoter of simian virus 40 in vitro. The two related human LBP-1 genes are TFCP2A, which encodes the alternatively spliced transcripts LBP-1a and LBP-1b, and TFCP2C, which encodes LBP-1c and LBP-1d. LBP-9, also designated transcription factor CP2-like 1 (TFCP2L1), is a protein of 479 amino acids. LBP-9 shows 83% sequenceCP2相关转录抑制因子1抗体 homology with LBP-1b and acts as a suppressor factor inhibiting the stimulation effect of LBP-1b. LBP-9 may regulate the P450scc reporter activity through the -155/-131 element. Function: Transcriptional suppressor. May suppress UBP1-mediated transcriptional activation. Modulates the placental expression of CYP11A1. Subcellular Location: Nucleus. Tissue Specificity: Highly expressed in placental JEG-3 cells and CP2相关转录抑制因子1抗体very low levels of expression in non-steroidogenic cells. No expression was seen in adrenal NCI-H295A cells or in adrenal tissue. Similarity: Belongs to the grh/CP2 family. CP2 subfamily. Gene ID: 29842 Database links: Entrez Gene: 29842 Human Entrez Gene: 81879 Mouse Omim: 609785 Human SwissProt: Q9NZI6 Human SwissProt: Q3UNW5 Mouse Unigene: 156471 Human Unigene: 24621 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
CP2相关转录抑制因子1抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 结合蛋白 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid