磷酸二酯酶9A抗体
规格：1mg/1ml
英文名： PDE9A
别名： 5''-cyclic phosphodiesterase 9A; cGMP specific 3' 5' cyclic phosphodiesterase type 9; CGMP-specific 3'5'-cyclic phosphodiesterase type 9; FLJ90181; High affinity cGMP-specific 3''; High-affinity cGMP-
分子量： 70-73kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human PDE9A
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：细胞浆
磷酸二酯酶9A抗体产品介绍：background: The protein encoded by this gene catalyzes the hydrolysis of cAMP and cGMP to their corresponding monophosphates. The encoded protein plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes. Subcellular Location: Cytoplasm. Endoplasmic reticulum; Cell projection > ruffle membrane. Cytoplasm > perinuclear region and Cell projection > ruffle membrane. Cytoplasm >磷酸二酯酶9A抗体 perinuclear region. Golgi apparatus. Endoplasmic reticulum. Tissue Specificity: Expressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily. Gene ID: 5152 Database links: Entrez Gene: 5152 Human Entrez Gene: 18585 Mouse Entrez Gene: 191569 Rat GenBank: 磷酸二酯酶9A抗体NP_001001567.1 Human Omim: 602973 Human SwissProt: O76083 Human SwissProt: O76083-2 Human SwissProt: O70628 Mouse Unigene: 473927 Human Unigene: 10812 Mouse Unigene: 20981 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸二酯酶9A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid