精神分裂症与犰狳重复基因抗体
规格：1mg/1ml
英文名： ARVCF
别名： Armadillo repeat gene deletes in velocardiofacial syndrome; Armadillo repeat protein; Armadillo repeat protein deleted in velo cardio facial syndrome; Armadillo repeat protein deleted in velo-cardio-f
分子量： 105kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ARVCF
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位：
精神分裂症与犰狳重复基因抗体产品介绍：background: Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes, which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS), a relatively common human disorder with phenotypic features including 精神分裂症与犰狳重复基因抗体cleft palate, conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs, a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition, ARVCF contains a predicted nuclear-targeting sequence suggesting that精神分裂症与犰狳重复基因抗体 it may have a function as a nuclear protein. [provided by RefSeq, Jun 2010]. Function: Involved in protein-protein interactions at adherens junctions. Subunit: Interacts (via the extreme C-terminus) with FRMPD2 (via the PDZ 2 domain). Tissue Specificity: Found in all the examined tissues including heart, brain, liver and kidney. Found at low level in lung. Similarity: Belongs to the beta-catenin family. Contains 10 ARM repeats. Gene ID: 421 Database links: Entrez Gene: 421 Human Omim: 602269 Human SwissProt: O00192 Human Unigene: 699354 Human Unigene: 713616 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
精神分裂症与犰狳重复基因抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid