肌动蛋白相关蛋白2/3亚型1A抗体
规格:1mg/1ml
英文名: ARPC1A
别名: Actin binding protein (Schizosaccharomyces pombe sop2 like); Actin related protein 2/3 complex subunit 1A 41kDa; Actin-related protein 2/3 complex subunit 1A; ARC1A_HUMAN; Arc40; ARPC1A; SOP2-like pro
分子量: 42kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ARPC1A
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞浆
肌动蛋白相关蛋白2/3亚型1A抗体产品介绍:background: This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex.肌动蛋白相关蛋白2/3亚型1A抗体 Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]. Function: Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating肌动蛋白相关蛋白2/3亚型1A抗体 nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Subunit: Probable component of the Arp2/3 complex in which it may replace ARPC1B. Subcellular Location: Cytoplasm; cytoskeleton. Similarity: Belongs to the WD repeat ARPC1 family. Contains 6 WD repeats. Database links: UniProtKB/Swiss-Prot: Q92747.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肌动蛋白相关蛋白2/3亚型1A抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 细胞骨架
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid