ADP核糖基化因子相关蛋白1
规格：1mg/1ml
英文名： ARFRP1
别名： ADP ribosylation factor related protein 1; ARF related protein 1; ARF related protein; ARL 18; ARL18; ARP 1; ARP; ARP1; Helicase like protein NHL; MGC6837; SCG10 like protein; ARFRP_HUMAN.
分子量： 23kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ARFRP1
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Sheep,
细胞定位：细胞浆
ADP核糖基化因子相关蛋白1产品介绍：background: The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells and they play a central role in the maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D (PC-PLD). ARFRP1 (ADP-ribosylation factor related protein 1), also known as ARP or ARL18, is a 201 amino acid membrane-associated GTPase that localizes to the plasma membrane and the Golgi apparatus and is related to the ARF family of regulatory proteins. Expressed in a ADP核糖基化因子相关蛋白1variety of tissues, ARFRP1 interacts with SYS1 and is thought to be involved in plasma membrane-related signaling events. ARFRP1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to a gene cluster on chromosome 20 that is commonly overexpressed in tumors, suggesting a role for ARFRP1 in carcinogenesis. Function: ARFRP1 (ARF related protein 1) is a membrane-associated GTP-ase and localizes to the plasma membrane. It is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) genes. ARFPR1 isADP核糖基化因子相关蛋白1 possibly involved in plasma membrane related signaling events. ARFRP1 interacts with SYS1 and is located in Golgi and found in most tissues. Subunit: Interacts with SYS1. Subcellular Location: Golgi Apparatus Tissue Specificity: Found in most tissues. Similarity: Belongs to the small GTPase superfamily. Arf family. Database links: UniProtKB/Swiss-Prot: Q13795.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ADP核糖基化因子相关蛋白1产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转运蛋白 糖蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid