生长终止特异性同源盒基因抗体
规格：1mg/1ml
英文名： Gax
别名： growth arrest-specific homeobox; Homeobox protein MOX-2; Mesenchyme homeobox 2; mesenchyme homeobox 2-like; Growth arrest-specific homeobox; GAX; growth arrest homeobox transcription factor GAX; mesen
分子量： 33kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Gax
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
细胞定位：
生长终止特异性同源盒基因抗体产品介绍：background: This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed生长终止特异性同源盒基因抗体 in Alzheimers disease. Function: Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle (By similarity). Subunit: Interacts with RNF10. Subcellular Location: Nucleus. Nucleus speckle. Similarity: Contains 1生长终止特异性同源盒基因抗体 homeobox DNA-binding domain. Gene ID: 4223 Database links: Entrez Gene: 4223 Human Entrez Gene: 17286 Mouse Entrez Gene: 29279 Rat Omim: 600535 Human SwissProt: P50222 Human SwissProt: P32443 Mouse SwissProt: P39020 Rat Unigene: 170355 Human Unigene: 341398 Mouse Unigene: 34890 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Gax主要在血管平滑肌细胞和内皮细胞中表达的同源异形盒基因,但Gax基因过表达可以抑制血管平滑肌细胞和内皮细胞的增殖，Gax也是脊椎动物肢体发育的重要调节因子，目前除用于心血管方面的研究，也用于肿瘤血管方面的探索。
生长终止特异性同源盒基因抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid