膜粘连蛋白11抗体
规格：1mg/1ml
英文名： Annexin A11
别名： 56 kDa autoantigen; Annexin A11; Annexin XI; Annexin-11; AnnexinA11; AnnexinXI; ANX 11; ANX A11; ANX11; ANX11_HUMAN; ANXA 11; ANXA11; Autoantigen 56 kD; Calcyclin associated annexin 50; Calcyclin-asso
分子量： 54kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Annexin
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
膜粘连蛋白11抗体产品介绍：background: The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain, which binds to phospholipids in a Ca2+-dependent manner, and a unique amino terminal region, which may confer binding specificity. The annexin family has been implicated as regulators of such diverse processes as ion-flux, endocytosis and exocytosis, and cellular adhesion. Two forms of Annexin XI, designated A and B, have been identified. Transfection of COS-7膜粘连蛋白11抗体 cells with Annexin XI-A, but not Annexin XI-B, causes formation of Annexin XI-associated vesicles. Function: Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis. Subunit: Interacts with S100A6 (By similarity). Interacts with PDCD6 in a calcium-dependent manner. Interacts with KIF23 during cytokinesis. Subcellular膜粘连蛋白11抗体 Location: Cytoplasm. Melanosome. Nucleus envelope. Nucleus > nucleoplasm. Cytoplasm > cytoskeleton > spindle. Found throughout the nucleoplasm at interphase and during mitosis concentrates around the mitotic apparatus (By similarity). Elevation of intracellular calcium causes relocalization from the nucleoplasm to the nuclear envelope, with little effect on the cytoplasmic pool. Localization to the nuclear envelope is cell-cycle dependent. Similarity: Belongs to the annexin family. Contains 4 annexin repeats. Database links: UniProtKB/Swiss-Prot: P50995.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
膜粘连蛋白11抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 通道蛋白 细胞粘附分子 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid