可溶性附着蛋白α-SNAP抗体
规格:1mg/1ml
英文名: Alpha SNAP
别名: Alpha soluble NSF attachment protein; Alpha-soluble NSF attachment protein; N ethylmaleimide sensitive factor attachment protein alpha; N-ethylmaleimide-sensitive factor attachment protein alpha; NAPA
分子量: 33kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human Alpha SN
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位:细胞膜
可溶性附着蛋白α-SNAP抗体产品介绍:background: Syntaxins were originally thought to be docking proteins, but have more recently been categorized as anchoring proteins that anchor themselves to the cytoplasmic surfaces of cellular membranes. Syntaxins have been shown to bind to various proteins involved in exocytosis, including VAMPs (vesicle-associated membrane proteins), NSF (N-ethylmaleimide-sensitive factor), SNAP 25 (synaptosomal-associated protein of 25kDa), SNAPs (soluble NSF attachment proteins) and synaptotagmin. VAMPs可溶性附着蛋白α-SNAP抗体 (also designated synaptobrevins), including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. Subunit: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8 (By similarity). Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12 (By similarity). Subcellular Location: Membrane; Peripheral membrane protein. Similarity: Belongs to the SNAP可溶性附着蛋白α-SNAP抗体 family. Gene ID: 8775 Database links: Entrez Gene: 518407 Cow Entrez Gene: 8775 Human Entrez Gene: 108124 Mouse Entrez Gene: 140673 Rat Omim: 603215 Human SwissProt: P81125 Cow SwissProt: P54920 Human SwissProt: Q9DB05 Mouse SwissProt: P54921 Rat Unigene: 126938 Human Unigene: 727492 Human Unigene: 104540 Mouse Unigene: 431371 Mouse Unigene: 31745 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
可溶性附着蛋白α-SNAP抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 转运蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid