γ-氨基丁酸醛脱氢酶抗体
规格:1mg/1ml
英文名: ALDH9A1
别名: 4 trimethylaminobutyraldehyde dehydrogenase; 4-trimethylaminobutyraldehyde dehydrogenase; AL9A1_HUMAN; aldehyde dehydrogenase (NAD+); Aldehyde dehydrogenase 9A1; Aldehyde dehydrogenase E3 isozyme; Ald
分子量: 54kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ALDH9A1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞浆
γ-氨基丁酸醛脱氢酶抗体产品介绍:background: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in ***** liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation ofγ-氨基丁酸醛脱氢酶抗体 a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction. Function: Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction. Subunit: Homotetramer. Subcellular Location: Cytoplasm. Tissue Specificity: High expression in ***** liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain. Expressed in all regions of the brain. Expression levels are variable in the different brain areas,γ-氨基丁酸醛脱氢酶抗体 with the highest levels in the spinal cord and the lowest in the occipital pole. Post-translational modifications: The N-terminus is blocked. Similarity: Belongs to the aldehyde dehydrogenase family. Gene ID: 233 Database links: Entrez Gene: 223 Human Entrez Gene: 56752 Mouse Entrez Gene: 64040 Rat Omim: 602733 Human SwissProt: P49189 Human SwissProt: Q9JLJ2 Mouse SwissProt: Q9JLJ3 Rat Unigene: 2533 Human Unigene: 330055 Mouse Unigene: 474999 Mouse Unigene: 98155 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
γ-氨基丁酸醛脱氢酶抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 神经生物学 信号转导 新陈代谢 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid