乙醇脱氢酶5抗体
规格：1mg/1ml
英文名： ADH5
别名： ADH 3; ADH5; ADHX; ADHX_HUMAN; Alcohol dehydrogenase (class III) chi polypeptide; alcohol dehydrogenase 5 (class III) chi polypeptide; Alcohol dehydrogenase 5; Alcohol dehydrogenase class 3; Alcohol d
分子量： 40kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ADH5
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
乙醇脱氢酶5抗体产品介绍：background: The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via乙醇脱氢酶5抗体 its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans. Function: Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl)乙醇脱氢酶5抗体 glutathione. Subunit: Homodimer. Subcellular Location: Cytoplasm. Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. Gene ID: 128 Database links: Entrez Gene: 128 Human Entrez Gene: 11532 Mouse Entrez Gene: 100145871 Rat Omim: 103710 Human SwissProt: P11766 Human SwissProt: P28474 Mouse SwissProt: P12711 Rat Unigene: 78989 Human Unigene: 3874 Mouse Unigene: 222115 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
乙醇脱氢酶5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid