酪蛋白激酶casein kinase Iα抗体
规格：1mg/1ml
英文名： Caseine Kinase 1 alpha
别名： Casein kinase 1 alpha 1; Casein kinase I isoform alpha; CK1; CK1A; CKI alpha; CKI-alpha; CKIa; Clock regulator kinase; Csnk1a1; Down regulated in lung cancer; HLCDGP1; KC1A_HUMAN; PRO2975.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CK1A/Cas
交叉反应：Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核 细胞浆
酪蛋白激酶casein kinase Iα抗体产品介绍：background: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis. Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling.酪蛋白激酶casein kinase Iα抗体 Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis. Subunit: Monomer. Interacts with the Axin complex. Interacts with TUT1, leading to TUT1 phosphorylation. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle. Note=Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis. Similarity: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. Contains 酪蛋白激酶casein kinase Iα抗体1 protein kinase domain. Database links: UniProtKB/Swiss-Prot: P48729.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
酪蛋白激酶casein kinase Iα抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid