胃癌多药耐药相关蛋白
规格：1mg/1ml
英文名： CAPRIN2
别名： C1q domain-containing protein 1; C1QDC1; CAPR2_HUMAN; Caprin family member 2; Caprin-2; caprin2; Cytoplasmic activation/proliferation-associated protein 2; EEG 1; EEG1; Gastric cancer multidrug resist
分子量： 126kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CAPRIN2
交叉反应：Human, Mouse, Rat, Chicken, Pig, Horse, Sheep,
细胞定位：细胞浆
胃癌多药耐药相关蛋白产品介绍：background: Caprin2 is 1127 amino acid highly conserved protein that is ubiquitously expressed with highest levels of expression in brain and spleen. Caprin2 stabilizes cytosolic β-catenin and enhances LEF-1 dependent reporter gene activity as well as the expression of Wnt target genes in mammalian cells. Caprin2 promotes LRP5/6 phosphorylation by GSK-3 and enhances the interaction between Axin and LRP5/6. It is suggested that Caprin2 functions as a proapoptotic inhibitor of the cell cycle. Nine isoforms of Caprin2 exist 胃癌多药耐药相关蛋白due to alternative splicing events. Function: May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. Subcellular Location: Cytoplasm; Mitochondrion.胃癌多药耐药相关蛋白 Colocalizes with aggregated mitochondria and Mitochondrion. Cytoplasm. Expressed throughout the cytoplasm. Tissue Specificity: Detected in all tissues tested with highest levels of expression in brain and spleen. Similarity: Belongs to the caprin family. Contains 1 C1q domain. Database links: UniProtKB/Swiss-Prot: Q6IMN6.1 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胃癌多药耐药相关蛋白产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 干细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid