血红素氧合酶2抗体
规格：1mg/1ml
英文名： HO-2
别名： Heme oxygenase (decycling) 2; Heme oxygenase (decyclizing) 2; HMOX 2; HMOX2; HMOX2 protein; HO 2; HO2; HMOX2_HUMAN.
分子量： 36kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HO-2
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
血红素氧合酶2抗体产品介绍：background: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter. Summary: catalyzes the conversion of heme to biliverdin; involved in cellular response to oxidative stress [SUBCELLULAR LOCATION] Microsome. Endoplasmic reticulum. [INDUCTION] Heme oxygenase 2 activity is non-inducible. [SIMILARITY] Belongs to the heme oxygenase family. Function: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form血红素氧合酶2抗体 biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Heme oxygenase 2 could be implicated in the production of carbon monoxide in brain where it could act as a neurotransmitter. Subcellular Location: Microsome. Endoplasmic reticulum. Similarity: Belongs to the heme oxygenase family. Contains 2 HRM (heme regulatory motif) repeats. Gene ID: 3163 Database links: Entrez Gene: 510243 Cow 血红素氧合酶2抗体Entrez Gene: 479864 Dog Entrez Gene: 3163 Human Entrez Gene: 15369 Mouse Entrez Gene: 100009523 Rabbit Entrez Gene: 79239 Rat Omim: 141251 Human SwissProt: P30519 Human SwissProt: O70252 Mouse SwissProt: P43242 Rabbit SwissProt: P23711 Rat Unigene: 284279 Human Unigene: 272866 Mouse Unigene: 10241 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 合成与降解（Synthesis and Degradation） 血红素氧合酶是目前发现生物体内*易被诱导产生的抗氧化酶类，其抗氧化作用与它的催化分解产物即胆绿素、胆红素、NO、铁离子和铁蛋白有关。 血红素氧合酶-2基因缺失对血红素诱导的氧化应激性导致的组织损伤具有保护作用;选择性抑制神经元血红素氧合酶-2基因的表达可减轻氧化应激性组织细胞损伤.
血红素氧合酶2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 神经生物学 合成与降解
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid