FAM65B蛋白抗体
规格：1mg/1ml
英文名： FAM65B
别名： Ab2 162; C6orf32; DIFF48; FA65B_HUMAN; Fam65b; KIAA0386; PL48; Protein FAM65B.
分子量： 118kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAM65B
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞浆
FAM65B蛋白抗体产品介绍：background: Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome FAM65B蛋白抗体6. The C6orf32 gene product has been provisionally designated C6orf32 pending further characterization. Function: Isoform 2 play a role in promoting myogenic cell differentiation, cytoskeletal rearrangement and filopodia formation. Subcellular Location: Mitochondrion and Cytoplasm; cytoskeleton. Cell projection; filopodium. Detected in cellular filopodia. Tissue Specificity: Isoform 1 is present in the brain. Isoform 2 is FAM65B蛋白抗体expressed during differentiation of fetal primary myoblasts. Also shows marked expression during cytotrophoblast differentiation. Post-translational modifications: Asn-41 was reported (PubMed:16335952) to be N-glycosylated; however as this position is probably not extracellular, the in vivo relevance is not proven. Similarity: Belongs to the FAM65 family. Database links: UniProtKB/Swiss-Prot: Q9Y4F9.4 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FAM65B蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 发育生物学 干细胞 糖尿病
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid