γ2肌动蛋白抗体
规格:1mg/1ml
英文名: ACTG2
别名: ACT; ACTA3; ACTE; Actin gamma 2 smooth muscle enteric; Actin gamma enteric smooth muscle; Actin like protein; ACTL3; ACTSG; Alpha actin 3; Gamma 2 actin; Smooth muscle gamma actin; ACTH_HUMAN.
分子量: 42kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ACTG2/Ga
交叉反应:Human, Mouse, Rat, Chicken, Pig, Cow, Rabbit,
细胞定位:细胞浆
γ2肌动蛋白抗体产品介绍:background: Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N terminal peptides. Function: Actins are highly conserved proteins that are involved in various γ2肌动蛋白抗体types of cell motility and are ubiquitously expressed in all eukaryotic cells. Subunit: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Subcellular Location: Cytoplasm: cytoskeleton Post-translational modifications: Oxidation of Met-45 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. Methionine sulfoxide is produced stereospecifically, but it is not known whether the (S)-S-oxide or the (R)-S-oxide is produced (By similarity)γ2肌动蛋白抗体. Similarity: Belongs to the actin family. Gene ID: 72 Database links: Entrez Gene: 72 Human Entrez Gene: 11468 Mouse Entrez Gene: 25365 Rat Entrez Gene: 396084 Chicken Entrez Gene: 281595 Cow Omim: 102545 Human SwissProt: P63270 Chicken SwissProt: Q5E9B5 Cow SwissProt: P63267 Human SwissProt: P63268 Mouse SwissProt: P63269 Rat Unigene: 516105 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
γ2肌动蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 细胞骨架 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid