血管非炎性蛋白2抗体
规格：1mg/1ml
英文名： VNN2
别名： FOAP 4; FOAP-4; Glycosylphosphatidyl inositol-anchored protein GPI-80; GPI 80; GPI-80; OTTHUMP00000017228; OTTHUMP00000233789; OTTHUMP00000233791; pantetheinase; Protein FOAP-4; vanin 2; Vanin-2; Vann
分子量： 59kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human VNN2
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
血管非炎性蛋白2抗体产品介绍：background: Vanin-2 is a 520 amino acid GPI-anchor protein that belongs to the CN hydrolase family and BTD/VNN subfamily.Widely expressed with high expression in spleen and blood, vanin-2 is suggested to be involved in thymus homing of bone marrow cells, regulation of Integrin ∫2-mediated cell adhesion, and migration and motility of neutrophils. Vanin-2 exists as five alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 6q23.2. Function: This gene product is a member of the Vanin family of proteins which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and 血管非炎性蛋白2抗体membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Two transcript variants encoding different isoforms have been described for this gene. Subcellular Location: Cell Membrane; Lipid-anchor, GPI-anchor Tissue Specificity: Widely expressed 血管非炎性蛋白2抗体with higher expression in spleen and blood. Similarity: Belongs to the CN hydrolase family. BTD/VNN subfamily. Contains 1 CN hydrolase domain. Database links: UniProtKB/Swiss-Prot: O95498.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血管非炎性蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 心血管 发育生物学 干细胞 细胞粘附分子 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid