肿瘤坏死因子配体超家族成员7抗体
规格：1mg/1ml
英文名： CD70
别名： CD 27L; CD 70; CD27 L; CD27 LG; CD27 ligand; CD27-L; CD27L; CD27LG; CD70; CD70 antigen; CD70 molecule; CD70_HUMAN; Ki 24 antigen; Ki24 antigen; Surface antigen CD70; TNFSF 7; TNFSF7; Tumor necrosis fa
分子量： 21kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CD70/CD2
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞膜
肿瘤坏死因子配体超家族成员7抗体产品介绍：background: The tumor necrosis factor (TNF) receptor family is composed of several type I integral membrane glycoproteins that exhibit homology in their cystine-rich extracellular domains. Members of this family include FAS, OX40, CD27 and CD30. Ligands for these receptors are often type II transmembrane glycoproteins, as is the case for CD27 and CD30. CD27 is a homodimeric lymphocyte-specific surface antigen present on T and B lymphocytes. Activation of the CD3 complex via the T cell receptor for antigen leads to an increase in CD27 expression. Together, CD27 and its ligand, CD27L, generate co-stimulatory signals required for complete T肿瘤坏死因子配体超家族成员7抗体 cell activation. CD30 is a surface marker for neoplastic cells of the Hodgkin’s lymphoma and related hematologic malignancies. CD30L has been shown to enhance the proliferation of the Hodgkin’s cell line HDLM-2, but exerts antiproliferative effects on large cell anaplastic lymphoma cell lines. Function: Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation 肿瘤坏死因子配体超家族成员7抗体of costimulated T-cells and enhances the generation of cytolytic T-cells. Subcellular Location: Membrane. Similarity: Belongs to the tumor necrosis factor family. Database links: Entrez Gene: 970 Human Omim: 602840 Human SwissProt: P32970 Human Unigene: 501497 Human Unigene: 715224 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤坏死因子配体超家族成员7抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 干细胞 生长因子和** **细胞 t-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid