囊泡转运蛋白Use1抗体
规格：1mg/1ml
英文名： USE1
别名： 2010315L10Rik; 5730403H22Rik; AV002165; D12; Ed2; Embryonic development factor 2; MDS032; P31; Protein D12; Protein p31; putative MAPK activating protein PM26; Putative MAPK-activating protein PM26; Q
分子量： 29kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human USE1
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞浆 细胞膜
囊泡转运蛋白Use1抗体产品介绍：background: In eukaryotic cells, the Golgi apparatus receives newly synthesized proteins from the endoplasmic reticulum (ER) and, after covalent modification, delivers them to their destination in the cell. For membrane-directed proteins this process is believed to be carried out via vesicular transport. Correct vesicular transport is determined by specific pairing of vesicle-associated SNAREs (v-SNAREs) with those on the target membrane (t-SNAREs). Unconventional SNARE in the ER 1, also known as USE1 or protein p31, 囊泡转运蛋白Use1抗体is a 259 amino acid t-SNARE that forms a larger complex with ZW10, RINT-1 and Syntaxin 18. Upon Mg2+-AP treatment in the presence of NSF and ?SNAP, ZW10, RINT-1 and USE1 dissociate from Syntaxin 18. USE1 is a single-pass type IV membrane protein that is localized to the endoplasmic reticulum membrane. Three named isoforms exist for USE1 as a result of alternative splicing events. Function: SNARE that ma囊泡转运蛋白Use1抗体y be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER. Subunit: Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18. Subcellular Location: Endoplasmic reticulum membrane. Similarity: Belongs to the USE1 family. Database links: UniProtKB/Swiss-Prot: Q9NZ43.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
囊泡转运蛋白Use1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学 信号转导 干细胞 转录调节因子
储存条件： Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid