转录因子TBX6抗体
规格：1mg/1ml
英文名： TBX6
别名： DFNB 67; DFNB67; T box 6; T box protein 6; T box transcription factor TBX 6; T box transcription factor TBX6; T-box protein 6; T-box transcription factor TBX6; Tbox 6; TBX 6; tbx6; TBX6_HUMAN.
分子量： 47kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human TBX6 (24
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Rabbit,
细胞定位：细胞核
转录因子TBX6抗体产品介绍：background: Members of the T-box (Tbx) gene family share a conserved domain that codes for the T-box, a sequence involved in DNA-binding and protein dimerization. The Tbx gene family is largely conserved throughout metazoan evolution, and is implicated in a variety of developmental processes ranging from the formation of germ layers to the organizational patterning of the central nervous system. In the mouse, Tbx6 is involved in both the specification and patterning of the somites along the entire length of the embryo.转录因子TBX6抗体 Specifically, Tbx6 is expressed in the primitive streak, tail bud, and presomitic mesoderm and is essential for the specification of posterior paraxial mesoderm. In the absence of Tbx6, posterior somites are replaced by ectopic neural tubes. Function: Probable transcriptional regulator involved in developmental processes. Could be required for specification of paraxial mesoderm structures during gastrulation.转录因子TBX6抗体 Subunit: Forms a dimeric complex with DNA (in vitro). Subcellular Location: Nucleus. Tissue Specificity: Expressed in fetal tail bud, posterior spinal tissue, intervertebral disk and testis. Also expressed in ***** testis, kidney, lung, muscle and thymus. Similarity: Contains 1 T-box DNA-binding domain. Database links: UniProtKB/Swiss-Prot: O95947.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
转录因子TBX6抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学 干细胞 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid