核转录因子抗体
规格：1mg/1ml
英文名： SOX1
别名： sex determining region Y box 1; sox1; SOX1_HUMAN; SRY; SOX-1; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1.
分子量： 39kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Human SOX6
交叉反应：Human, Mouse, Pig,
细胞定位：细胞核
核转录因子抗体产品介绍：background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. 核转录因子抗体At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Function: Transcriptional activator. Subcellular Location: Nucleus. Tissue Specificity: Mainly expressed in the developing central nervous system. Post-translational modifications: 核转录因子抗体Sumoylation inhibits the transcriptional activity. Similarity: Contains 1 HMG box DNA-binding domain. Database links: Entrez Gene: 6656 Human Entrez Gene: 20664 Mouse Omim: 602148 Human SwissProt: O00570 Human SwissProt: P53783 Mouse Unigene: 202526 Human Unigene: 39088 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
核转录因子抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：发育生物学 神经生物学 干细胞 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid